ABSTRACT The discovery of Piezo channels, mechanosensitive proteins that transduce physical pressure into cellular signals, formally validated the relationship between touch and proprioception. It is now clear that the manual therapist’s touch directly engages the same mechanosensitive pathways that mediate spatial awareness. For structural integration, this finding holds special significance, as it establishes proprioception as equal in importance to structure and movement. This new scientific understanding reveals how proprioception in structural integration through touch, combined with body-wide spatial awareness, forms a powerful combination. Given the complexity of spatial processing in relation to balance, systematic spatial awareness training may help optimize balance. To that end, the novel concept of propriosphere is introduced as a three-dimensional visual model around a client to establish spatial reference points for sensing balance. The author also develops the concept of propriosomatics, exercises and movements specifically aimed at improving proprioception. Using balance as the fundamental organizing principle, the Rolfing® Ten Series thus becomes a progression of spatial and neurological information that transforms postural organization, movement patterns, and sensory awareness.