ABSTRACT Contraindication lists give guidance to manual therapy practitioners regarding how to handle the symptoms and conditions that they may encounter with their clients. This July 2023 issue of Structure, Function, Integration focuses on autoimmune disorders and the considerations that structural integration (SI) practitioners, in particular, need to consider when working with people with any of these conditions. Topics discussed include whether we have to refer these clients elsewhere every time, whether SI can help people with autoimmune conditions, and what specific cautions are warranted. Rolfers often have clients with complex medical histories, including autoimmune diagnoses, and they may still benefit from this work.